Have you ever heard of John Leal? He's basically why we have clean drinking water. He, almost single-handedly eradicated typhoid fever and waterborne sickness in the U.S.
Even better, he started with a major risk: he didn't tell any authorities and, in almost complete secrecy, started experimenting with chlorine in water supplies. It easily could have ruined him.
The risk of being ruined is how we often defeat the resistance to change.